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Co-solvent Enhancement Calculation

Estimates the solubility enhancement factor (E) for a solute in supercritical CO2 when a polar co-solvent is added, based on modified solubility parameters.

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1. Define Input Parameters

2. Engineering Output

Baseline CO2 Solubility Parameter (delta_CO2)
- MPa^0.5
Co-solvent Volume Fraction (phi_cs)
- dimensionless
Mixed Solvent Solubility Parameter (delta_mix)
- MPa^0.5
Solubility Enhancement Factor (E_factor)
- dimensionless

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Context & Assumptions

The Co-solvent Enhancement calculation is a fundamental procedure in Supercritical Fluid Extraction used to estimate the solubility increase of a target solute when a polar entrainer is added to a supercritical carbon dioxide stream. This method allows process engineers to determine optimal solvent formulations and extraction efficiencies without requiring complex equation-of-state modeling. It is particularly useful during the preliminary scoping phase of solvent design for polar or high-molecular-weight compounds.

Understand the Engineering Principles

Review the step-by-step derivations, typical industrial limits, and scale-up rules.

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